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Independent publications

Thorat, R. G.; Brooks, B.; Nichols, B.; Harned, A. M. Stereoselective synthesis of the C14–C23 fragment of biselyngbyolide A and B enabled by transition metal catalysis. Tetrahedron 201874, 7277–7281. (abstract) (Part of a special issue titled Recent Applications of Metal Catalysis in Natural Product Synthesis)

Tang, T.; Moon, N. G.; McKay, L.; Harned, A. M. A New Strategy to Access Enantioenriched Cyclohexadienones: Kinetic Resolution of para-Quinols by Organocatalytic thiol-Michael Addition Reactions. ACS Omega 20183, 15492–15500. (abstract)

Tang, T.; Harned, A. M. Experimental evidence for the formation of cationic intermediates during iodine(III)-mediated oxidative dearomatization of phenols. Org. Biomol. Chem. 2018, 16, 8249–8252. (abstract) (Part of a themed collection on Mechanistic, computational & physical organic chemistry in OBC)

Harned, A. M. From determination of enantiopurity to the construction of complex molecules: The Horeau principle and its application in synthesis. Tetrahedron 201874, 3797–3841. (abstract)

Moon, N. G.; Harned, A. M. Synthetic explorations of the briarane jungle: Progress in developing a synthetic route to a common family of diterpenoid natural products. Royal Society Open Science 20185, 172280, DOI: 10.1098/rsos.172280. (abstract)

Harned, A. M. Concerning the Mechanism of Iodine(III)-Mediated Oxidative Dearomatization of Phenols. Org. Biomol. Chem. 2018, 16, 2324–2329. (abstract)

Thorat, R. G.; Harned, A. M. Rapid, enantioselective synthesis of the C1–C13 fragment of biselyngbyolide B. Chem. Commun. 201854, 241–243. (abstract)

Moon, N. G.; Harned, A. M. Torsional Steering as Friend and Foe: Development of a Synthetic Route to the Briarane Diterpenoid Stereotetrad. Org. Biomol. Chem. 201715, 1876–1888. (abstract)

Volp, K. A.; Harned, A. M. Total Synthesis of Sorbicillactone A: An Inspiration for Methodology and Catalyst Development. In Strategies and Tactics in Organic Synthesis; Harmata, M., Ed. Elsevier: London, 2015, Vol. 11, pp 253–308. (abstract)

Moon, N. G.; Harned, A. M. A Concise Synthetic Route to the Stereotetrad Core of the Briarane Diterpenoids. Org. Lett. 2015, 17, 2218–2221. (abstract)

Harned, A. M. α-Alkylation of a norbornene-derived tricyclic ketone: are steric factors really in control? Chem. Commun. 2015, 51, 2076–2079. (abstract)

Kalstabakken, K. A.; Harned, A. M. Asymmetric transformations of achiral 2,5-cyclohexadienones. Tetrahedron 2014,70, 9571–9585. (Invited report article) (abstract)

Harned, A. M. Asymmetric oxidative dearomatizations promoted by hypervalent iodine(III) reagents: an opportunity for rational catalyst design? Tetrahedron Lett. 201455, 4681–4689. (Invited digest article) (abstract)

Volp, K. A.; Harned, A. M. Origin of Stereoselectivity of the Alkylation of Cyclohexadienone-Derived Bicyclic Malonates. J. Org. Chem. 201378, 7554–7564. (abstract)

Tello-Aburto, R.; Kalstabakken, K. A.; Harned, A. M. Ligand and Substrate Effects During Pd-Catalyzed Cyclizations of Alkyne-Tethered Cyclohexadienones. Org. Biomol. Chem. 201311, 5596–5604. (abstract)

Kalstabakken, K. A.; Harned, A. M. Spectral Database for Instructors: A Living, Online NMR FID Database. J. Chem. Ed. 201390, 941–943. (abstract)

Moon, N. G.; Harned, A. M. Iodine(III)-promoted synthesis of oxazolines from N-allylamides. Tetrahedron Lett. 201354, 2960–2963. (abstract)

Volp, K. A.; Harned, A. M. Chiral Aryl Iodide Catalysts for the Enantioselective Synthesis of para-Quinols. Chem. Commun. 201349, 3001–3003. (abstract)

Hexum, J. K.; Tello-Aburto, R.; Struntz, N. B.; Harned, A. M.; Harki, D. A. Bicyclic Cyclohexenones as Inhibitors of NF-κB Signaling. ACS Med. Chem. Lett. 20123, 459–464. (abstract)

Harned, A. M.; Volp, K. A. The sorbicillinoid family of natural products: Isolation, biosynthesis, and synthetic studies.Nat. Prod. Rep. 201128, 1790–1810. (abstract)

Tello-Aburto, R.; Kalstabakken, K. A.; Volp, K. A.; Harned, A. M. Regioselective and Stereoselective Cyclization of Cyclohexadienones Tethered to Active Methylene Groups. Org. Biomol. Chem. 20119, 7849–7859. (abstract)(Featured in the top 10% of the most highly cited articles published in the Impact Factor window for 2011-2012)

Volp, K. A.; Johnson, D. M.; Harned, A. M. A Concise Synthetic Approach to the Sorbicillactones: Total Synthesis of Sobicillactone A and 9-epi-Sorbicillactone A. Org. Lett. 201113, 4486–4489. (abstract)

Lang, P. T.; Harned, A. M.; Wissinger, J. E. Oxidation of Borneol to Camphor using Oxone and Catalytic Sodium Chloride: A Green Experiment for the Undergraduate Organic Chemistry Laboratory. J. Chem. Ed. 201188, 652–656. (abstract)

Rout, L.; Harned, A. M. Allene Carboxylates as Dipolarophiles in Rh-Catalyzed Carbonyl Ylide Cycloadditions. Chem. Eur. J. 200915, 12926–12928. (abstract)

Tello-Aburto, R.; Harned, A. M. Palladium-Catalyzed Reactions of Cyclohexadienones: Regioselective Cyclizations Triggered by Alkyne Acetoxylation. Org. Lett. 200911, 3998–4000. (abstract)

Publications from graduate and postdoctoral work

Harned, A. M.; Stoltz, B. M. Development of a catalytic enantioselective synthesis of the guanacastepene and heptemerone tricyclic core. Tetrahedron 2019, DOI: 10.1016/j.tet.2019.02.053. (abstract) (Part of a special issue in honor of Ryan Shenvi’s receipt of the Tetrahedron Young Investigator Award)

Craig, R. A., II; Loskot, S. A.; Mohr, J. T.; Behenna, D. C.; Harned, A. M.; Stoltz, B. M. Palladium-Catalyzed Enantioselective Decarboxylative Allylic Alkylation of Cyclopentanones. Org. Lett. 2015, 17, 5160–5163. (abstract)

Bennett, N. B.; Hong, A. Y.; Harned, A. M.; Stoltz, B. M. Synthesis of Enantioenriched γ-Quaternary Cycloheptenones Using a Combined Allylic Alkylation/Stork–Danheiser Approach: Preparation of Mono-, Bi-, and Tricyclic Systems.Org. Biomol. Chem. 201210, 56–59. (abstract)

Hong, A. Y.; Bennett, N. B.; Krout, M. R.; Jensen, T.; Harned, A. M.; Stoltz, B. M. Palladium-Catalyzed Asymmetric Alkylation in the Synthesis of Cyclopentanoid and Cycloheptanoid Core Structures Bearing All-Carbon Quaternary Stereocenters. Tetrahedron 201167, 10234–10248. (Special issue in honor of Gilbert Stork) (abstract)

Behenna, D. C.; Mohr, J. T.; Sherden, N. H.; Marinescu, S. C.; Harned, A. M.; Tani, K.; Seto, M.; Ma, S.; Novák, Z.; Krout, M. R.; McFadden, R. M.; Roizen, J. L.; Enquist, J. A. Jr.; White, D. E.; Levine, S. R.; Petrova, K. V.; Iwashita, A.; Virgil, S. C.; Stoltz, B. M. Enantioselective Decarboxylative Alkylation Reactions: Catalyst Development, Substrate Scope, and Mechanistic Studies. Chem.—Eur. J. 201117, 14199–14223. (abstract)

Hong, A. Y.; Krout, M. R.; Jensen, T.; Bennett, N. B.; Harned, A. M.; Stoltz, B. M. Ring-Contraction Strategy for the Practical, Scalable, Catalytic Asymmetric Synthesis of Versatile γ-Quaternary Acylcyclopentenes. Angew. Chem. Int. Ed. 201150, 2756–2760. (abstract) (Angew. Chem. 2011123, 2808–2812)

Mohr, J. T.; Behenna, D. C.; Harned, A. M.; Stoltz, B. M. Deracemization of Quaternary Stereocenters by Pd-Catalyzed Enantioconvergent Decarboxylative Allylation of Racemic β-Ketoesters. Angew. Chem. Int. Ed. 200544, 6924–6927. (abstract) (Angew. Chem. 2005117, 7084–7087)

Harned, A. M; Sherrill, W. M.; Flynn, D. L.; Hanson, P.R. High-Load, Soluble Oligomeric Benzenesulfonyl Azide: Application to Facile Diazo-Transfer Reactions. Tetrahedron 200561, 12093–12099. (abstract)

Harned, A. M; Zhang, M.; Vedantham, P.; Mukherjee, S.; Herpel, R.H.; Flynn, D. L.; Hanson, P. R. ROM Polymerization in Facilitated Synthesis. Aldrichimica Acta 200538, 3–16. (paper)

Harned, A. M.; He, H. S.; Toy, P. H.; Flynn, D. L.; Hanson, P. R. Multipolymer Solution-Phase Reactions: Application to the Mitsunobu Reaction. J. Am. Chem. Soc. 2005127, 52–53. (abstract)

Harned, A. M.; Probst, D. A.; Hanson, P.R. The Use of Olefin Metathesis in Combinatorial Chemistry: Supported and Chromatography-Free Syntheses. In Handbook of Metathesis; Grubbs, R. H., Ed.; Wiley-VCH: New York, 2003; Vol 2., pp 361–402. (book description)

Harned, A. M.; Mukherjee, S.; Flynn, D. L.; Hanson, P. R. Ring-Opening Metathesis Phase-Trafficking (ROMpt) Synthesis: Multistep Synthesis on Soluble ROM Supports. Org. Lett. 20035, 15–18. (abstract)

Harned, A. M.; Hanson, P. R.; Flynn, D. L. Natural Product Synthesis Utilizing Solid-Supporting Reagents. Chemtracts200215, 630–636. (summary)

Moore, J. D.; Harned, A. M.; Henle, J.; Flynn, D. L.; Hanson, P. R.Scavenge-ROMP–Filter: A Facile Strategy for Soluble Scavenging via Norbornenyl Tagging of Electrophilic Reagents. Org. Lett. 20024, 1847–1849. (abstract)

Harned, A. M.; Hanson, P. R. Capture-ROMP–Release: Application for the Synthesis of O-Alkylhydroxylamines. Org. Lett. 20024, 1007–1010. (abstract)

Wanner, J.; Harned, A. M.; Probst, D. A.; Poon, K. W. C.; Klein, T. A.; Snelgrove, K. A.; Hanson, P. R. A Dual Metathesis Route to Oligomeric Sulfonamides. Tetrahedron Lett. 200243, 917–921. (abstract)